Cytogenetic Technologist Career

Job Description: Analyze chromosomes or chromosome segments found in biological specimens, such as amniotic fluids, bone marrow, solid tumors, and blood to aid in the study, diagnosis, classification, or treatment of inherited or acquired genetic diseases. Conduct analyses through classical cytogenetic, fluorescent in situ hybridization (FISH) or array comparative genome hybridization (aCGH) techniques.


Is Cytogenetic Technologist the right career path for you?
Take the MyMajors Quiz and find out if it fits one of your top recommended majors!

Cytogenetic Technologist Career

What Cytogenetic Technologists do:

  • Analyze chromosomes found in biological specimens to aid diagnoses and treatments for genetic diseases such as congenital disabilities, fertility problems, and hematological disorders.
  • Arrange and attach chromosomes in numbered pairs on karyotype charts, using standard genetics laboratory practices and nomenclature, to identify normal or abnormal chromosomes.
  • Count numbers of chromosomes and identify the structural abnormalities by viewing culture slides through microscopes, light microscopes, or photomicroscopes.
  • Create chromosome images using computer imaging systems.
  • Determine optimal time sequences and methods for manual or robotic cell harvests.
  • Develop and implement training programs for trainees, medical students, resident physicians or post-doctoral fellows.
  • Evaluate appropriateness of received specimens for requested tests.
  • Examine chromosomes found in biological specimens to detect abnormalities.
  • Harvest cell cultures using substances such as mitotic arrestants, cell releasing agents, and cell fixatives.
  • Identify appropriate methods of specimen collection, preservation, or transport.
  • Input details of specimen processing, analysis, and technical issues into logs or laboratory information systems (LIS).
  • Input details of specimens into logs or computer systems.
  • Prepare biological specimens such as amniotic fluids, bone marrow, tumors, chorionic villi, and blood, for chromosome examinations.
  • Prepare slides of cell cultures following standard procedures.
  • Select appropriate culturing system or procedure based on specimen type and reason for referral.
  • Select or prepare specimens and media for cell cultures using aseptic techniques, knowledge of medium components, or cell nutritional requirements.
  • Stain slides to make chromosomes visible for microscopy.
  • Summarize test results and report to appropriate authorities.
  • Describe chromosome, FISH and aCGH analysis results in International System of Cytogenetic Nomenclature (ISCN) language.
  • Develop, implement, and monitor quality control and quality assurance programs to ensure accurate and precise test performance and reports.
  • Maintain laboratory equipment such as photomicroscopes, inverted microscopes, and standard darkroom equipment.
  • Select appropriate methods of preparation and storage of media to maintain potential of hydrogen (pH), sterility, or ability to support growth.
  • Archive case documentation and study materials as required by regulations and laws.
  • Select banding methods to permit identification of chromosome pairs.
  • Supervise subordinate laboratory staff.
  • Communicate to responsible parties unacceptable specimens and suggest remediation for future submissions.
  • Apply prepared specimen and control to appropriate grid, run instrumentation, and produce analyzable results.
  • Recognize and report abnormalities in the color, size, shape, composition, or pattern of cells.
  • Extract, measure, dilute as appropriate, label, and prepare DNA for array analysis.
  • Communicate test results or technical information to patients, physicians, family members, or researchers.

What work activities are most important?

Importance Activities

Documenting/Recording Information - Entering, transcribing, recording, storing, or maintaining information in written or electronic/magnetic form.

Updating and Using Relevant Knowledge - Keeping up-to-date technically and applying new knowledge to your job.

Communicating with Supervisors, Peers, or Subordinates - Providing information to supervisors, co-workers, and subordinates by telephone, in written form, e-mail, or in person.

Analyzing Data or Information - Identifying the underlying principles, reasons, or facts of information by breaking down information or data into separate parts.

Getting Information - Observing, receiving, and otherwise obtaining information from all relevant sources.

Identifying Objects, Actions, and Events - Identifying information by categorizing, estimating, recognizing differences or similarities, and detecting changes in circumstances or events.

Working with Computers - Using computers and computer systems (including hardware and software) to program, write software, set up functions, enter data, or process information.

Processing Information - Compiling, coding, categorizing, calculating, tabulating, auditing, or verifying information or data.

Organizing, Planning, and Prioritizing Work - Developing specific goals and plans to prioritize, organize, and accomplish your work.

Interpreting the Meaning of Information for Others - Translating or explaining what information means and how it can be used.

Inspecting Equipment, Structures, or Materials - Inspecting equipment, structures, or materials to identify the cause of errors or other problems or defects.

Making Decisions and Solving Problems - Analyzing information and evaluating results to choose the best solution and solve problems.

Monitoring Processes, Materials, or Surroundings - Monitoring and reviewing information from materials, events, or the environment, to detect or assess problems.

Evaluating Information to Determine Compliance with Standards - Using relevant information and individual judgment to determine whether events or processes comply with laws, regulations, or standards.

Establishing and Maintaining Interpersonal Relationships - Developing constructive and cooperative working relationships with others, and maintaining them over time.

Controlling Machines and Processes - Using either control mechanisms or direct physical activity to operate machines or processes (not including computers or vehicles).

Training and Teaching Others - Identifying the educational needs of others, developing formal educational or training programs or classes, and teaching or instructing others.

Coordinating the Work and Activities of Others - Getting members of a group to work together to accomplish tasks.

Handling and Moving Objects - Using hands and arms in handling, installing, positioning, and moving materials, and manipulating things.

Performing Administrative Activities - Performing day-to-day administrative tasks such as maintaining information files and processing paperwork.

Coaching and Developing Others - Identifying the developmental needs of others and coaching, mentoring, or otherwise helping others to improve their knowledge or skills.

Developing and Building Teams - Encouraging and building mutual trust, respect, and cooperation among team members.

Scheduling Work and Activities - Scheduling events, programs, and activities, as well as the work of others.

Judging the Qualities of Objects, Services, or People - Assessing the value, importance, or quality of things or people.

Estimating the Quantifiable Characteristics of Products, Events, or Information - Estimating sizes, distances, and quantities; or determining time, costs, resources, or materials needed to perform a work activity.

Monitoring and Controlling Resources - Monitoring and controlling resources and overseeing the spending of money.

Providing Consultation and Advice to Others - Providing guidance and expert advice to management or other groups on technical, systems-, or process-related topics.

Guiding, Directing, and Motivating Subordinates - Providing guidance and direction to subordinates, including setting performance standards and monitoring performance.

Thinking Creatively - Developing, designing, or creating new applications, ideas, relationships, systems, or products, including artistic contributions.

Repairing and Maintaining Electronic Equipment - Servicing, repairing, calibrating, regulating, fine-tuning, or testing machines, devices, and equipment that operate primarily on the basis of electrical or electronic (not mechanical) principles.

Developing Objectives and Strategies - Establishing long-range objectives and specifying the strategies and actions to achieve them.

Communicating with People Outside the Organization - Communicating with people outside the organization, representing the organization to customers, the public, government, and other external sources. This information can be exchanged in person, in writing, or by telephone or e-mail.

Resolving Conflicts and Negotiating with Others - Handling complaints, settling disputes, and resolving grievances and conflicts, or otherwise negotiating with others.

Holland Code Chart for a Cytogenetic Technologist